The Science Of The Endocannabinoid System

CBD oil has taken the wellness world by storm. For example, even though CBD is now legal in all 50 states, it can’t be marketed as a supplement or added to food products. If replicable, the study offers the first evidence-based explanation for how CBD works in the brain to counteract psychosis, with results that could help generate new treatments. Intensified side effects: It is well known that using alcohol in conjunction with any drug intensifies the side effects that occur with that drug.

Associated facts and figures are daunting: In Europe, chronic musculoskeletal pain of a disabling nature affects over one in four elderly people ( Frondini et al 2007 ), while figures from Australia note that older half of older people suffer persistent pain, and up to 80% in nursing home populations ( Gibson 2007 ). Responses to an ABC News poll in the USA indicated that 19% of adults (38 million) have chronic pain, and 6% (or 12 million) have utilized cannabis in attempts to treat it ( ABC News et al 2005 ).

The oral CBD spray used in studies have found it to have an NNT of 5.0, which is comparable to many routine agents used in treating neuropathic pain, including SSRIs (NNT 5.0) and gabapentin (NNT 6.4).10,11 A similar meta-analysis of 18 double-blind, randomized controlled trials on the efficacy of CBD also showed modest cannabinoid analgesia, but also analyzed the harms associated with CBD.

When a product is called hemp oil, it is usually in reference to the oil derived CBD oil from the seeds of the Cannabis Sativa plant. Customer service pointed out that the same CBD oil is used for all their products, but since potencies do vary, we appreciate companies that show potency testing for all products. As an increasing number of US states have legalized the use of marijuana, CBD oil is also becoming readily available.